Role of the Sweet Taste Receptor in Glucose Metabolism: No Sweets for Diabetes?
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چکیده
منابع مشابه
Disordered Control of Intestinal Sweet Taste Receptor Expression and Glucose Absorption in Type 2 Diabetes
We previously established that the intestinal sweet taste receptors (STRs), T1R2 and T1R3, were expressed in distinct epithelial cells in the human proximal intestine and that their transcript levels varied with glycemic status in patients with type 2 diabetes. Here we determined whether STR expression was 1) acutely regulated by changes in luminal and systemic glucose levels, 2) disordered in ...
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15 صفحه اولHumans Can Taste Glucose Oligomers Independent of the hT1R2/hT1R3 Sweet Taste Receptor.
It is widely accepted that humans can taste mono- and disaccharides as sweet substances, but they cannot taste longer chain oligo- and polysaccharides. From the evolutionary standpoint, the ability to taste starch or its oligomeric hydrolysis products would be highly adaptive, given their nutritional value. Here, we report that humans can taste glucose oligomer preparations (average degree of p...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2015
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.14-00250-1